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How do PXP systems work?

While the efficiency of Bone Marrow Concentrate (BMC) Therapy is undeniable, historically, the biggest hurdle these treatments have to face are the complications to collect BMC that is free of Red Blood Cell Contamination and other elements that affect the final efficacy of the treatment.

medical testing

However, thanks to the introduction of the PXP System, clinicians now count on a reliable and efficient method to harvest BMC without having to spend long periods or having to worry about the contamination levels per sample. But how do PXP systems work? What is the secret behind this breakthrough? And what are its practical applications? Let’s take a look at it and find out.

The Basics of PXP Systems

The PXP System is defined as a semi-automated system designed to harvest precise volumes of a cell concentrate from bone marrow aspirate. In short, it’s a system that can generate Bone Marrow Concentrate in just 20 minutes and with a depletion rate of up to 98% for contaminating Red Blood Cells.

So the Thermogenesis PXP System is a fast and highly efficient method to harvest and filter concentrate, but how does it work, and why does it reach this level of efficiency? To answer this, we need to look at the different components present in PXP Systems.

The first element and the one clinicians will need to interact with the most is the Disposable Cartridge. This large cartridge can accept both traditional samples and pre-processed ones with ease. Inside the cartridge, there are separate chambers for BMC and RBC, meaning that the system largely relies on centrifugation to separate its samples. However, thanks to its multi-sensor detection technology, PXP Systems can separate the samples with higher efficiency.

Each Disposable Cartridge is loaded on top of a Control Module, which counts with advanced sensor technology designed to assist in separating BMC and RBC. Each Contro Module is small and fits perfectly as the Cartridge base, and these two components are designed to be loaded together on a centrifuge. Combining the centrifuge work with the sensors in the Control Module, a PXP System can separate BMC in just 20 minutes, and the concentrate will be ready to be harvested from its independent chamber in the Disposable cartridge.

But the process does not end there, as there are two additional components we must cover to explain PXP Systems fully. On the one hand, we have the Docking Station. By loading a Control Module onto it and connecting the Station with a PC, the system allows experts to analyze the processed samples and the process itself. And to make this even easier, the last component is the DataTrak Software, designed to work with the Control Module and speed up data analysis.

In Summary

Thermogenesis’ PXP System is a complete solution that takes the basic centrifugation concept and expands on it through its unique design. This refined design and, in particular, its sensor technology allows for superior results in BMC harvesting and promise a brighter feature for Bone Marrow Concentrate Therapy. On top of that, since it requires no additional installation and it’s largely self-reliant, making the switch to PXP Systems is fast and straightforward.

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